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KMID : 1140420210300040377
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Journal of Obesity & Metabolic Syndrome
2021 Volume.30 No. 4 p.377 ~ p.385
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Short-term Mortality and Postoperative Complications of Abdominal Aortic Aneurysm Repair in Obese versus Non-obese Patients
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Zonneveld Bo
Vu Duyen
Kardys Isabella
van Dalen Bas M.
Snelder Sanne M.
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Abstract
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Background: Obesity is a risk factor not only for abdominal aortic aneurysm (AAA) but also for complications after vascular surgery. This study was to determine the effect of obesity on short-term mortality and post-intervention complications after AAA repair.
Methods: A systematic review and meta-analysis were performed. A systematic search was performed in PubMed; the articles describing the differences in post-intervention complications after open or endovascular repair of an AAA between obese and non-obese patients were selected. The primary outcome was short-term mortality defined as in-hospital mortality or mortality within 30 days after AAA repair. The secondary outcomes were cardiac complications, pulmonary failure, renal failure, and wound infections. The meta-analysis was performed using OpenMeta.
Results: Four articles were included in the meta-analysis; these articles included 35,989 patients of which 10,917 (30.3%) were obese. The meta-analysis showed no significant differences for short-term mortality (odds ratio [OR], 0.85; 95% confidence interval [CI], 0.69?1.04). Also, no significant difference was found in pulmonary failure (OR, 1.09; 95% CI, 0.85?1.42). However, obese patients were less likely to suffer from cardiac complications (OR, 0.73; 95% CI, 0.55?0.96). Nevertheless, there was a significantly higher risk of renal failure (OR, 1.16; 95% CI, 1.05?1.30) and wound infections (OR, 1.92; 95% CI, 1.55?2.38) in obese patients.
Conclusion: Obesity is not a risk factor for short-term mortality after AAA repair compared to non-obesity. Moreover, obese patients suffer less from cardiac complications than non-obese patients.
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KEYWORD
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Obesity, Abdominal aortic aneurysm, Postoperative complications, Mortality
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